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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63107 | Anti-inflammatory agent 6 | ||
Anti-inflammatory agent 6 exhibits anti-inflammatory potential by blocking the phosphorylation of Iκb kinase α/β (IKKα/β), IκBα and nuclear factor kB p65 (NF-κb p65), which are key controllers of inflammation. | |||
T75174 | Anti-inflammatory agent 42 | IL Receptor , TNF | |
Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages. | |||
T64359 | Anti-inflammatory agent 36 | Immunology/Inflammation related | |
Anti-inflammatory agent 36 is an anti-inflammatory agent. It exhibited dose-dependent inhibition of LPS-induced release of TNF-a and IL-6 in active RAW 264.7 mouse macrophages, IC50=3.69uM and 3.68uM, respectively. | |||
Fr12277 | 4-Hydroxy-6-methylcoumarin | Others | |
4-Hydroxy-6-methylcoumarin (4-HMC) is a naturally occurring phenolic compound, a derivative of coumarin, found in a variety of plants, fungi, and bacteria. It has anti-inflammatory and anti-tumor activity.4-HMC is used a... | |||
T2787 | Picroside I | 6'-Cinnamoylcatalpol | MMP , STAT |
Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug ... | |||
T3794 | Pentagalloylglucose | Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose | Influenza Virus |
1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten... | |||
T6S0139 | Neobavaisoflavone | Apoptosis , DNA/RNA Synthesis | |
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si... | |||
T0798 | Triamcinolone | Fluoxyprednisolone,Aristocort,Rodinolone | Glucocorticoid Receptor , COX |
Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca... | |||
T83058 | Anti-inflammatory agent 44 | ||
Compound 1 (Anti-inflammatory agent 44) is a 6-methoxyflavonol glycoside exhibiting anti-inflammatory properties, and it can be extracted from the aerial parts of Tetragonia tetragonoides [1]. | |||
T61302 | Anti-inflammatory agent 17 | ||
Anti-inflammatory agent 17 an orally active anti-inflammatory agent, demonstrates potent efficacy in inhibiting the release of IL-6 and TNF-α without causing cytotoxicity in in vitro experiments. Furthermore, in vivo stu... | |||
T83048 | Anti-inflammatory agent 64 | ROS Kinase | |
Anti-inflammatory agent 64 (compound 4b) exhibits antioxidant and anti-inflammatory activities, effectively inhibiting the secretion of IL-6 and TNF-α while also reducing paw edema [1] in both in vitro and in vivo studie... | |||
T72144 | 6-trans-12-epi-Leukotriene B4 | ||
6-trans-12-epi-Leukotriene B4, a metabolite of arachidonic acid, serves as a potent anti-inflammatory agent. | |||
T83059 | Anti-inflammatory agent 43 | ||
Compound 43, also known as compound 3, is a 6-methoxyflavonol glycoside exhibiting anti-inflammatory activity. This agent, along with compound 44, is extractable from the aerial parts of Tetragonia tetragonoides [1]. | |||
T72413 | Antimicrobial agent-6 | ||
Antimicrobial Agent-6, exhibiting a minimum inhibitory concentration (MIC) range of 4-8 μg/mL, is effective against both gram-positive and gram-negative bacteria. Additionally, it demonstrates anti-inflammatory propertie... | |||
T79620 | Anti-inflammatory agent 55 | ||
Compound 9j (anti-inflammatory agent 55), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression of iNOS, TNF-α, IL-6, and IL-1β. It notably suppresses LPS-... | |||
T63873 | Anti-Aβ agent 1A | ||
Anti-Aβ agent 1A is a potent anti-amyloid-β agent. Anti-Aβ agent 1A significantly inhibits LPS-induced IL-1β, IL-6 and TNF-α levels and reduces H2O2-induced apoptosis in SH-SY5Y cells using the mitochondrial pathway, exh... | |||
T79585 | Anti-inflammatory agent 50 | NF-κB | |
Anti-inflammatory agent 50 (compound a1), a derivative of Fusidic acid, exerts its effects through inhibition of inflammatory mediators including NO, IL-6, and TNF-α. It mitigates acute lung injury by modulating these me... | |||
T79619 | Anti-inflammatory agent 54 | ||
Anti-inflammatory agent 54 (compound 9c), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression of pro-inflammatory cytokines such as iNOS, TNF-α, IL-6, an... | |||
T79992 | Sarglaroids F | Caspase | |
Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+ efflux and diminishing Caspase-1(P20) concentrations. Additional... | |||
T60433 | NF-κB-IN-6 | ||
NF-κB-IN-6 (Compound 3d) is an anti-inflammatory agent that works by reducing the protein expression of iNOS and COX-2 by suppressing the NF-κB signaling pathway. NF-κB-IN-6 inhibits the production of NO in LPS-induced R... |